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eight (mCD8) as a adverse handle or RAIDD and after that treated with ZM447439 for either 24 h and processed for immunoblotting (C) or up to 72 h and processed for DNA content evaluation (D).minor or no up-regulation of the proapoptotic p53 targets PUMA and BAX was observed upon either Nultin-3 treatment or cytokinesis failure. Surprisingly, when the identical treatment options were carried out in


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